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Wei Fan Selected Research

Methionine Adenosyltransferase

1/2022Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease.
1/2021Deregulated 14-3-3ζ and methionine adenosyltransferase α1 interplay promotes liver cancer tumorigenesis in mice and humans.
11/2020Reciprocal Regulation Between Forkhead Box M1/NF-κB and Methionine Adenosyltransferase 1A Drives Liver Cancer.
1/2016Deregulated methionine adenosyltransferase α1, c-Myc, and Maf proteins together promote cholangiocarcinoma growth in mice and humans(‡).

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Wei Fan Research Topics

Disease

98Neoplasms (Cancer)
08/2022 - 08/2003
21Breast Neoplasms (Breast Cancer)
06/2022 - 07/2004
16Infections
01/2022 - 06/2001
15Nasopharyngeal Carcinoma
01/2022 - 03/2002
15Neoplasm Metastasis (Metastasis)
01/2018 - 03/2002
13Hepatocellular Carcinoma (Hepatoma)
01/2022 - 04/2008
11Inflammation (Inflammations)
07/2022 - 11/2002
9Rheumatoid Arthritis
12/2021 - 01/2008
9Carcinogenesis
01/2021 - 07/2010
8Lymphoma (Lymphomas)
04/2021 - 04/2009
8Lymphatic Metastasis
01/2018 - 08/2003
7Liver Neoplasms (Liver Cancer)
01/2022 - 01/2016
6Cataract (Cataracts)
08/2022 - 07/2018
6Prostatic Neoplasms (Prostate Cancer)
10/2020 - 04/2007
6Hypoxia (Hypoxemia)
10/2019 - 03/2006
5Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 07/2015
5Seizures (Absence Seizure)
01/2022 - 06/2009
5Pain (Aches)
01/2022 - 11/2006
5Wounds and Injuries (Trauma)
10/2021 - 01/2013
5Cholangiocarcinoma
01/2021 - 01/2016
5Colorectal Neoplasms (Colorectal Cancer)
09/2019 - 08/2003
5Epilepsy (Aura)
10/2013 - 12/2011
4Myopia
08/2022 - 09/2020
4Neurodegenerative Diseases (Neurodegenerative Disease)
03/2022 - 01/2019
4Stroke (Strokes)
01/2022 - 06/2013
4Lung Neoplasms (Lung Cancer)
01/2022 - 04/2005
4Carcinoma (Carcinomatosis)
01/2021 - 08/2003
4Poisoning
01/2021 - 01/2013
4Adenocarcinoma
11/2020 - 10/2016
4Macular Degeneration (Age-Related Maculopathy)
01/2019 - 08/2003
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2018 - 05/2014
3Starvation
11/2022 - 01/2020
3Fibrosis (Cirrhosis)
09/2022 - 01/2014
3Colonic Neoplasms (Colon Cancer)
04/2022 - 11/2016
3Liver Diseases (Liver Disease)
01/2022 - 01/2014
3Body Weight (Weight, Body)
12/2021 - 01/2012
3Burkitt Lymphoma (Burkitt's Lymphoma)
12/2021 - 12/2015
3Intervertebral Disc Degeneration
01/2021 - 01/2019
3Dehydration (Water Stress)
01/2021 - 08/2011
3Pancreatic Neoplasms (Pancreatic Cancer)
08/2020 - 04/2014
3Ischemia
10/2019 - 01/2014
3Pancreatitis
01/2019 - 03/2007
3Type 2 Diabetes Mellitus (MODY)
12/2018 - 01/2008

Drug/Important Bio-Agent (IBA)

21Proteins (Proteins, Gene)FDA Link
09/2022 - 11/2002
20Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
12/2021 - 03/2007
18Pharmaceutical PreparationsIBA
01/2022 - 01/2011
14Biological ProductsIBA
04/2022 - 11/2004
12Biomarkers (Surrogate Marker)IBA
08/2022 - 04/2013
11Peptides (Polypeptides)IBA
10/2020 - 01/2012
9DNA (Deoxyribonucleic Acid)IBA
01/2021 - 03/2011
8LigandsIBA
01/2021 - 01/2011
8Messenger RNA (mRNA)IBA
01/2019 - 12/2003
7Glucose (Dextrose)FDA LinkGeneric
11/2022 - 01/2013
7SaponinsIBA
08/2016 - 01/2014
7MicroRNAs (MicroRNA)IBA
02/2016 - 01/2011
6CytokinesIBA
05/2022 - 09/2006
6Cysteine (L-Cysteine)FDA Link
04/2022 - 01/2012
5Paclitaxel (Taxol)FDA LinkGeneric
08/2022 - 01/2013
5CathepsinsIBA
04/2022 - 10/2018
5RadiopharmaceuticalsIBA
04/2022 - 11/2015
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2022 - 11/2004
5LipidsIBA
01/2022 - 02/2014
5EnzymesIBA
01/2022 - 01/2015
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2019 - 01/2014
5MicellesIBA
01/2019 - 01/2013
5AntigensIBA
01/2018 - 01/2011
4Neurotensin Receptors (Neurotensin Receptor)IBA
04/2022 - 11/2015
4Interleukin-6 (Interleukin 6)IBA
01/2022 - 09/2013
4Methionine AdenosyltransferaseIBA
01/2022 - 01/2016
4RNA (Ribonucleic Acid)IBA
01/2022 - 12/2003
4Retinaldehyde (Retinal)IBA
01/2022 - 01/2014
4Long Noncoding RNAIBA
10/2020 - 01/2017
4Glutamine (L-Glutamine)FDA Link
08/2016 - 01/2013
4Complement System Proteins (Complement)IBA
02/2015 - 08/2003
3Lactic Acid (Lactate)FDA LinkGeneric
11/2022 - 01/2013
3Monoclonal AntibodiesIBA
08/2022 - 01/2011
3Mitogen-Activated Protein KinasesIBA
08/2022 - 06/2015
3Estrogen ReceptorsIBA
06/2022 - 07/2004
3Progesterone Receptors (Progesterone Receptor)IBA
06/2022 - 01/2014
3AntioxidantsIBA
01/2022 - 06/2012
3Transcription Factors (Transcription Factor)IBA
01/2022 - 06/2014
3Hormones (Hormone)IBA
01/2022 - 01/2019
3Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA
01/2022 - 10/2018
3Glutamic Acid (Glutamate)FDA Link
01/2022 - 01/2013
3CalciumIBA
01/2022 - 01/2019
3VaccinesIBA
03/2021 - 05/2014
3ZeolitesIBA
01/2021 - 08/2011
3Phosphorus (Red Phosphorus)IBA
01/2021 - 01/2019
3hydroxypropyl methacrylateIBA
10/2020 - 10/2016
3IntegrinsIBA
08/2020 - 01/2019
3NAD (NADH)IBA
01/2020 - 07/2010
3Cisplatin (Platino)FDA LinkGeneric
06/2019 - 12/2003
3Oxygen (Dioxygen)IBA
01/2019 - 03/2012

Therapy/Procedure

35Therapeutics
07/2022 - 04/2008
12Drug Therapy (Chemotherapy)
12/2021 - 12/2003
8Radiotherapy
06/2022 - 03/2006
5Chinese Traditional Medicine (Traditional Chinese Medicine)
02/2020 - 03/2004
4Phacoemulsification
08/2022 - 07/2018
4Lasers (Laser)
11/2018 - 09/2016
3Renal Dialysis (Hemodialysis)
01/2021 - 01/2017